Researchers for the U.S. National Institute on Aging (NIA), a component of the National Institutes of Health (NIH), studied 5,614 Italians in four villages and found that those who scored high for antagonistic traits on a standard personality test had greater thickening of the neck (carotid) arteries compared to people who were more agreeable. Thickness of neck artery walls is a risk factor for heart attack and stroke.
Three years later, those who scored higher on antagonism or low agreeableness — especially those who were manipulative and quick to express anger — continued to have thickening of their artery walls. These traits also predicted greater progression of arterial thickening.
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